5-Minute Clinical Consult: Jaundice

Jaundice

Description

Jaundice is derived from the French word jaune, which means “yellow.”
Jaundice: A yellow or green/yellow hue to the skin, sclera, and mucous membranes that can be appreciated at serum bilirubin levels >2 mg/dL. Intensity of color is related directly to the serum bilirubin level.
Unconjugated bilirubin: 80% is due to hemoglobin turnover and 20% is from degradation of hepatic and renal heme proteins. It is a hydrophobic compound that must be carried to the liver by albumin for processing.
Conjugated bilirubin: Conjugated to glucuronic acid in the liver, a water-soluble derivative that helps lipid emulsification and absorption
Conjugated hyperbilirubinemia (direct hyperbilirubinemia): A conjugated bilirubin of >2 mg/dL or >20% of the total bilirubin.

Jaundice has been found in Select 5-Minute Pediatrics Topics

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