5-Minute Clinical Consult: Erythema Nodosum

Erythema Nodosum

Etiology

Idiopathic: 37–60%
Bacterial: Streptococcal infections (most common cause in children), tuberculosis, leprosy, Yersinia enterocolitica, tularemia, Campylobacter, salmonella, Shigella, gonorrhea
Sarcoid
Drugs: Sulfonamides, oral contraceptives, bromides
Pregnancy
Deep fungal: Dermatophytes, coccidioidomycosis, histoplasmosis, blastomycosis
Viral/Chlamydial: Infectious mononucleosis, lymphogranuloma venereum, paravaccinia
Enteropathies: Ulcerative colitis, Crohn disease, Behçet disease (1), celiac disease (2)
Malignancies: Lymphoma/leukemia, sarcoma, post radiation therapy

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