First Line

• Treatment of any underlying or causative disease
• Withdrawal of any drugs that might be the cause
• For mild cases, symptomatic treatment is sufficient.

• Steroid use is controversial. Patients who have recurrent herpes-induced erythema mulitforme may benefit from acyclovir, which reduces the number of herpetic episodes. Other causative infections should be treated appropriately.
• Contraindications: Some underlying infections or health problems, such as diabetes, may contraindicate the use of steroids.
• Precautions: Refer to the manufacturer's profile of each drug.
• Significant possible interactions: Refer to the manufacturer's profile of each drug.