5-Minute Clinical Consult: Cirrhosis of the Liver

5-Minute Clinical Consult

Cirrhosis of the Liver

Description

A chronic disease in which liver cell injury causes inflammation, necrosis, and stellate cell activation. Fibrosis replaces normal liver tissue and destroys the liver’s vascular and lobular architecture, progressively diminishing blood flow and decreasing function. End result is liver failure and/or cancer.

ALERT
Geriatric Considerations

Jaundice and encephalopathy more common

Pediatric Considerations

Inborn errors of metabolism (e.g. tyrosinemia), congenital anomalies (e.g. biliary atresia)

Cirrhosis of the Liver has been found in 5-Minute Clinical Consult

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