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Arterial Gas Embolism

Etiology

  • Cerebral air embolism:
    • Air bubbles occlude the brain vasculature.
    • Intracranial pressure (ICP) increases.
    • Unequal distribution of blood in the brain causes hyperemia and ischemia.
    • Small bubbles irritate vascular wall, causing breakdown of blood–brain barrier; small size allows rapid absorption and may cause only brief interruption of cerebral blood flow.
    • Larger air bubbles take longer to absorb (up to several hours) and can cause primary ischemic injury with diffuse brain edema and increased ICP.
  • Coronary air embolism is caused by obstruction of coronary arteries by an air bubble.
    • Temporary ischemia of myocardium
    • Labile blood pressure (BP)
    • Arrhythmias
    • Cardiac failure and/or arrest
  • Obstruction is possible in any artery. Small emboli in the vessels of skeletal muscles and viscera are well tolerated.

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