Etiology
- Cerebral air embolism:
- Air bubbles occlude the brain vasculature.
- Intracranial pressure (ICP) increases.
- Unequal distribution of blood in the brain causes hyperemia and ischemia.
- Small bubbles irritate vascular wall, causing breakdown of blood–brain barrier; small size allows rapid absorption and may cause only brief interruption of cerebral blood flow.
- Larger air bubbles take longer to absorb (up to several hours) and can cause primary ischemic injury with diffuse brain edema and increased ICP.
- Coronary air embolism is caused by obstruction of coronary arteries by an air bubble.
- Temporary ischemia of myocardium
- Labile blood pressure (BP)
- Arrhythmias
- Cardiac failure and/or arrest
- Obstruction is possible in any artery. Small emboli in the vessels of skeletal muscles and viscera are well tolerated.
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